Y zeolite effect

When a sample solution containing various molecules slowly flows through the gel column, each molecule in the column simultaneously with two different motion: vertical downward movement and non-directed diffusion movement. Macromolecules due to a larger diameter, not easy to enter pores of the gel particles, but only the distribution between the particles, the moving down when eluted faster. After the addition to the proliferation of small molecules in the gel particle gap, you can also enter the pores of the gel particles that enter the gel phase in the process of moving down in a gel diffusion from the particle gap then enter another gel particles, so continue to enter and spread down the speed of small molecules behind the macromolecules so large molecules in the sample elutes from the column first, slower middle molecules, molecular sieve oxysiv smallest final outflows, a phenomenon called molecular sieve effect.